Chronic Diseases Drive the Need for Hydrogel-based Wound Sealants in the U.S.

22 Jun
2016

 
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The origin of hydrogel dressing (hydrated polymer) can be traced to the year 1950. Hydrated polymer was introduced to regulate the fluid exchange from the surface of a wound. They are available in 3 different forms, including amorphous hydrogel, impregnated hydrogel as well as sheet hydrogel. Sudden rise in infection, especially in the United States has increased the adoption rate of these products, say industry experts at Allied Market Research studying the consumption volume, growth, state –wise performance and size and share of the U.S. hydrogel dressing market.

Future of the Hydrogel dressing market  

There has been an increasing demand for hydrogel dressing particularly for highly flexible parts of the human body such as knees or elbows. A team of researchers have been working with Xuanhe Zhao, a Career Development Associate Professor in Department of Mechanical Engineering at MIT to develop dressings that keep the wound area in these flexible parts both intact and functioning. Zhao has developed a hydrogel matrix, that many companies active in the hydrogel dressing market call the Band-Aid of generation next. The sticky, gel like and stretchable material designed by him can incorporate temperature sensors, LED lights drug –delivering systems, as well as others.

This smart wound dressing can release drugs in response to temperature change in the skin and glows when the medicine runs low. Yuk, one of the co-authors of Zhao’s research paper said “It’s a very versatile matrix.” He further explained “The unique capability here is, when a sensor senses something different, like an abnormal increase in temperature, the device can on demand release drugs to that specific location and select a specific drug from one of the reservoirs, which can diffuse in the hydrogel matrix for sustained release over time.”

Entrepreneurs receive grants to discover smart solutions 
Entrepreneurs active in the U.S. hydrogel dressing market are receiving grants to further their innovation. In addition, big brands and venture capitalists in the United States are also seen investing in other countries such as Israel. Recently BioTime (NYSEMKT: BTX), made headlines, when its subsidiary company Cell Cure Neurosciences received approximately $2.2 million from the Israel Ministry of Economy & Industry The grant will offer continuous funding for developing a product called OpRegen, which is a cell –based therapeutic solution. 

Officials at BioTime reveal that the product in now in 1/2a phase, where the scientist are conducting the dose – escalation clinical study. This study aims at helping the researchers understand more about product safety as well as its effectiveness in different eye conditions. BioTime is headquartered in San Francisco Bay Area and has subsidiaries in countries including China as well as Singapore. The company has established a product development center in La Jolla, CA.

Get access to detailed information visit on: https://www.alliedmarketresearch.com/US-hydrogel-dressing-market

Wound healing hydrogel helps in skin regeneration 

It is difficult to heal a chronic skin wound. The conditions worsen when they gradually span a large area or when wounds do not heal due to certain health problems including lack of mobility.  A group of scientists from the famous University of California, based in Los Angeles claimed to have found an effective solution for chronic wounds. The team has worked to enhance the mechanism of skin regeneration by using a new material. This material tends to create a porous scaffold and helps the wound to heal faster and more efficiently. 

When doctors come across a skin wound that obstruct the healing and repairing process, they depend upon the water –based dressing called hydrogels. But, what they don’t realize is that besides protecting and keeping the wound hydrated it can help in skin regeneration. To improve the product performance, many educational institutes are also receiving grants. A ULCA team was recently funded for a similar project by the National Institutes of Health. The fund helped the researchers active in the hydrogel dressing market invent an advanced hydrogel that contains microporous annealed particles. When applied to a chronic wound, these particles create porous scaffolding that is further colonized by new cells. 

Nanofibrous hydrogels brings in hope for burn cases 
To make sure the burn wound heals effectively the dead tissues are removed. Following this a new skin tissue engineering & regeneration, while ensuring the wounds close fast to reduce the risk of scar formation as well as infection. However, a team of researchers at A*STAR highlighted that non-cytotoxic hydrogels and non-immunogenic with nanofibrous peptide, can now expedite and promote the epithelial regeneration twice as fast as wound Care dressings available in the market. 

Commenting on the recent development Charlotte Hauser working at A*STAR Institute of Bioengineering and Nanotechnology based in Singapore said "Our ultrashort peptide-based hydrogel virtually fulfills all the criteria essential for accelerated wound healing," says Hauser. "The hydrogel can provide a moist environment as a consequence of its extremely high water retention capacity of up to 99.9%, which, to our knowledge, is unmatched by currently available wound Care dressings."

At present the products used in burn care such as hydrocolloids, gauzes, films prepared from synthetic and natural material and others are definitely in need of change. For instance, Mepitel often used in burn care maintains the gaseous permeability but does not work effectively when it comes to the hydrated environment needed for healing the wound.   According to Charlotte Hauser the new products maintains transparency that allows the medical practitioners to observe the wound treatment during the recovery process. Introduction of advanced products are anticipated to create new opportunities for the hydrogel dressing market in years to come. 

 

 
Akhilesh Prabhugaonkar

Akhilesh Prabhugaonkar

Author's Bio- Akhilesh Prabhugaonkar holds a bachelor’s degree in Electronics Engineering from the reputed Vishwakarma Institute of Technology. He has a special interest in the fields of forensics, world history, international relations and foreign policy, sports, agriculture, astronomy, security, and oceanography. An ardent bibliophile and melophile, Akhilesh loves to write on topics of his interest and various other societal issues. This love for writing made him enter the professional world of content writing and pursue his career in this direction.

 
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