Single Cell Multiomics: An Ingenious Solution Revolutionizing Oncology and Drug Discovery

Highlights:

• Introduction
• Reasons for the growing adoption of single cell multiomics
• Product launches in the sector

Single cell multiomics refers to a set of technologies that help assess different features and measure various molecules of the same individual cell. It is an umbrella term that comprises multiple single cell sequencing techniques to analyze the transcriptome, genome, epigenome, and other such omics domains. Moreover, these methodologies are used to study the diverse modalities of the same cell, such as gene perturbation, DNA methylation, RNA expression, chromatin accessibility, etc. Owing to such a wide scope of research, single cell multiomics is widely applicable in fields like oncology, immunology, neurology, etc.

Increasing preference for single cell multiomics is accelerating sectoral growth

The single cell multiomics industry accounted for $2,175 million in 2020 and is anticipated to gather a revenue share of $15,261.19 million by 2030, citing a CAGR of 21.4% during 2021-2030. The rising utility of these innovative biotechnology techniques in medical research applications has boosted the revenue share of the industry. The ability of these methodologies to identify, characterize, and classify various cell types within a tissue culture helps scientists understand the minute differences in their structure and function. Moreover, the knowledge obtained from such studies enables researchers to dissect tumor heterogeneity and identify patient-specific biomarkers. In the last few years, these methodologies have played a major role in developing personalized drugs and therapies, especially for cancer treatment.

Moreover, single cell multiomics also aid in tracking the changes taking place at the cellular level, thus providing insights into how diseases develop over time. Based on the data collected through these processes, doctors can enhance their understanding of disease pathogenesis and complicated cell interactions. In recent times, there has been an increase in the use of advanced computational methods to simplify these procedures, which aid in unraveling the various relationships between different chemical-physical modalities.

Launch of advanced solutions by multinational conglomerates

In the post-pandemic period, the focus on medical technologies and biotechnology research has increased exponentially. Several governmental agencies, private companies, and academic institutes have invested heavily in R&D projects to increase the efficacy of these technologies. Some multinational giants have even launched novel products in the market to expand their footprint in the industry.

For instance, in June 2024, Mission Bio, a biotechnology company based in San Francisco, unveiled Tapestri® Single-cell Multiple Myeloma Multiomics Solution, specifically designed for multiple myeloma therapeutic development. Multiple myeloma, a type of blood cancer, has a high rate of relapse among patients, thus making most of the conventional treatment approaches ineffective. The press release issued by the company stated that this product offers holistic clonal and subclonal insights that aid medical practitioners in locating the true nature of the disease and understanding its evolution in the patient’s body. This ultimately assists companies in formulating effective medical strategies.

In October 2024, Proteintech Genomics, a major player in the biomedical industry, announced the launch of MultiPro® Human Discovery Panel, an antibody platform designed to promote single-cell multiomics research. The new solution enables scientists to profile more than 300 protein molecules and study the various cellular components, cytokines, signaling proteins, transcription factors, etc. As per several industry experts, this high-tech panel is anticipated to transform the landscape of genomics in the near future.

Winding up, the growth of the single cell multiomics industry is attributed to the rising use of advanced genetic engineering techniques in immunology and neurology. Moreover, the increasing applicability of these techniques in drug development and cancer research is predicted to impact the market positively in the coming period. Furthermore, the surge in demand for personalized healthcare treatments is anticipated to help the sector flourish in the near future.

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