Era of Smart Pills: RaniPill Offers Most Effective Alternative to Injections

From cars to homes and from speakers to simple medical tablets, every second object in our lives has become smarter due to the Midas touch of advanced technology. These next-generation pills do not need to sit tight till they get dissolved after swallowing.

A recently developed smart pill named RaniPill capsule is a novel robotic tablet that has the potential to replace injections containing large drug molecules such as proteins, peptides, and antibodies. As per the company, the RaniPill pass into the intestine after it has swallowed by a patient. As the surrounding pH levels in the intestine increases, the pill’s coating dissolves and the chemical reaction causes inflation in the pill similar to a balloon, which in turn, injects the dissolvable microneedle filled with the required drug directly into the wall of the intestine.

If we compare RaniPill to the conventional injections, this approach is regarded as the safest and most painless, as the area where the injections take place does not have severe pain receptors. The most fascinating point regarding the smart pill is that the entire tablet is as small as a regular fish oil capsule.

Mir Imran, the CEO, and Founder of the Rani Therapeutics, stated, “People tend to prefer taking pills than visiting doctors to get an injection. However, it is not possible to take all the drugs orally. For instance, most of the biologics such as insulin and the world’s highest-selling drug, Humira cannot be taken orally”. He added that after huge research and spending more than billions of investments to develop “oral biologics”, only Rani successfully demonstrated the most effective alternative to the injections.

Recently, the company demonstrated a successful human trial and before that, there were more than 100 animal studies were performed to test the effectiveness of the smart pill’s delivery potential. In fact, the study showed than Rani’s smart pill offers 100% effective alternative to the conventional injections. The human trial took place at a Clinical Research Organization (CRO) in Texas that involved about 10 participants and they were divided into two groups. One group of the participant has the pill while the other did not take any kind of medication and they were observed for results. After this, all 10 took the pill, which contained no drug and the results were observed for the capsule’s safety. The researcher took X-rays of every participant after the interval of half an hour. After the study, the patients did not report any discomfort, including signs of sensation when the pill inflated, when the pill injects the non-contents.

The company declared that other human trials will take place in the coming years and it will include the study of smart pill delivering the drug-filled needle. The company has entered in several agreements with several pharmaceutical companies to use the RaniPill to deliver the drug contents to patients. Moreover, it has announced to launch its dedicated molecule in the future. The company expects new trials and partnerships at the end of the year and throughout 2020.

Related Post